Functional neurosurgery is a neurosurgical procedure done for alleviating symptoms of various central nervous system disorders that do not have any gross anatomical abnormality. Functional neurosurgery needs a well-coordinated multidisciplinary team approach involving neuroanesthesiologists, neurologists, neurosurgeons, neurophysiologists, and neuropsychologists. Anesthesiologists face certain unique challenges while managing patients scheduled for functional neurosurgery. Conscious sedation and monitored anesthesia care continues to be the preferred anesthesia techniques for functional neurosurgery. Patient cooperation, constant monitoring, and observing for early diagnosis and management of complications are the key elements for the success of any functional neurosurgical procedure.